Calcium carbonate from an organic source( oyster shell)
Equivalent to elemental calcium-------------------- 500 mg
Vitamin D3 IP--------------------------------------------- 250 IU
Calcium and mineral intake is crucial during preganacy and lactation in order to have a healthy foetal growth and prevent maternal bone mass loss. Therapy : Calcium supplement
Mechanism of action/Effect:
Calcium is essential for the functional integrity of the nervous, muscular, and skeletal systems. It plays a role in normal cardiac function, renal function, respiration, blood coagulation, and cell membrane and capillary permeability. Also, calcium helps to regulate the release and storage of neurotransmitters and hormones, the uptake and binding of amino acids, absorption of vitamin B 12, and gastrin secretion. The major fraction (99%) of calcium is in the skeletal structure primarily as hydroxyapatite, Ca 10(PO 4) 6(OH) 2; small amounts of calcium carbonate and amorphous calcium phosphates are also present. The calcium of bone is in a constant exchange with the calcium of plasma. Since the metabolic functions of calcium are essential for life, when there is a disturbance in the calcium balance because of dietary deficiency or other causes, the stores of calcium in bone may be depleted to fill the body's more acute needs. Therefore, on a chronic basis, normal mineralization of bone depends on adequate amounts of total body calcium.
Absorption:
Approximately one-fifth to one-third of orally administered calcium is absorbed in the small intestine, depending on presence of vitamin D metabolites, pH in lumen and on dietary factors, such as calcium binding to fiber or phytates. Calcium absorption is increased when a calcium deficiency is present or when a patient is on a low-calcium diet. In patients with achlorhydria or hypochlorhydria, calcium absorption, especially with the carbonate salt, may be reduced.
Protein binding:
Moderate, approximately 45% in plasma.
Elimination:
Renal (20%) -The amount excreted in the urine varies with degree of calcium absorption and whether there is excessive bone loss or failure of renal conservation.
Fecal (80%) - Consists mainly of nonabsorbed calcium, with only a small amount of endogenous fecal calcium excreted.
Dosage:
Pregnancy: 2 to 3 tablets per day
Lactation: 2 to 3 tablets per day
Daily recommended intakes for calcium are generally defined as follows:
Persons |
U.S. |
Canada |
Infants and children |
400–800 |
250–550 |
4 to 6 years of age |
800 |
600 |
7 to 10 years of age |
800 |
700–1100 |
Adolescent and adult males |
800–1200 |
800–1100 |
Adolescent and adult females |
800–1200 |
700–1100 |
Pregnant females |
1200 |
1200–1500 |
Breast-feeding females |
1200 |
1200–1500 |
Presentation:
Box of 10X15’s